Assoc. Dr. Mehmet ÖZBİL's TÜSEB Group B R&D Project was Accepted

Our institute faculty member Assoc. Dr. Mehmet Özbil and Department of Molecular Biology and Genetics faculty member Prof. Dr. "Experimental and Antimicrobial Effects of Hazelnut Green Skin Extract Grown in Turkey" by Meltem Yeşilçimen Akbaş. The TÜSEB B Group R&D project titled "Computational Analysis" has been accepted. In this proposed project, the use of innovative techniques to obtain the extract from hazelnut green shells, and then the detailed antimicrobial effects of this extract by performing compound-target matching with holistic experimental and studies, and the potential use of hazelnut green shell extract as an antibiofilm agent. Computational analysis of the binding of phenolic compounds determined in hazelnut green peel extract to the antibacterial target DNA Gyrase A-B protein complex and to the antibiofilm targets ica A, ica D and fnb A proteins and the active molecule-interacting target protein relationship will be revealed for the first time in the literature. Through experimental analysis, the effects of these compounds will be proven in the laboratory environment and the first steps will be taken for effective product formulation. The project will also make a great contribution to sustainable production by utilizing approximately 300 thousand tons of green shell waste generated every year in our country, which is the world leader in hazelnut production.