Dr. Öğr. Üyesi Melike FIRLAK
Chemistry

Melike FIRLAK
Phone
+90 (262) 6053023
Email
mfirlakgtu.edu.tr
Office
Chemical Engineering, 251
Areas of interest
Analytical chemistry, Fluorescence sensors, Adsorption, Stimuli-responsive polymers and their applications, Drug release

Refereed journal papers

[19] J. G. Hardy, S. Sdepanian, A. F. Stowell, A. D. Aljohani, M. J. Allen, A. Anwar, D. Barton, J. V. Baum, D. Bird, A. Blaney, L. Brewster, D. Cheneler, O. Efremova, M. Entwistle, R. N. Esfahani, M. Firlak, A. Foito, L. Forciniti, S. A. Geissler, F. Guo, R. M. Hathout, Richard Jiang, P. Kevin, D. Leese, W. L. Low, S. Mayes, M. Mozafari, S. T. Murphy, H. Nguyen, C. N. M. Ntola, G. Okafo, A. Partington, T. A. K. Prescott, S. P. Price, S. Soliman, P. Sutar, D. Townsend, P. Trotter,  K. L. Wright, Potential for Chemistry in Multidisciplinary, Interdisciplinary, and Transdisciplinary Teaching Activities in Higher Education, J. Chem. Educ. 2021, XXXX, XXX, XXX-XXX, https://doi.org/10.1021/acs.jchemed.0c01363 .

[18] E. Kivrak, T. Pauzaite, N. A. Copeland, J. G. Hardy, P. Kara, M. Firlak, A. I. Yardimci, S. Yilmaz, F. Palaz, M. Ozsoz, Detection of CRISPR-Cas9-Mediated Mutations Using a Carbon Nanotube-Modified Electrochemical Genosensor, Biosensors 2021, 11, 17. https://doi.org/10.3390/bios11010017.

[17] Ashton, I. C. Appen, M. Firlak, N. E. Stanhope, C. E. Schmidt, W. R. Eisenstadt, B. Hur, J. G. Hardy, Wirelessly triggered bioactive molecule delivery from degradable electroactive polymer films. Polymer International, 2021; 70: 467–474, DOI: 10.1002/pi.6089.

[16] S. T. Mousavi, G. R. Harper, S. Municoy, M. D. Ashton, D. Townsend, G. H. K. Alsharif, V. K. Oikonomou, M. Firlak, S. Au‐Yong, B E. Murdock, G. R. Akien, N R. Halcovitch, S. J. Baldock ,M. Fazilati, O. V. Kolosov, B. J. Robinson, M. F. Desimone, J. G. Hardy, Electroactive Silk Fibroin Films for Electrochemically Enhanced Delivery of Drugs, Macromolecular Materials and Engineering, 2020, 202000130.

[15] F. Leone, M. Firlak, K. Challen, W. Bonnefin, B. Onida, K. Wright, J. G. Hardy. In situ crosslinking bionanocomposite hydrogels for wound healing. Journal of Functional Biomaterials, 10, 50. DOI:10.3390/jfb10040050

[14] N. Tasci, S. Cubuk, M. Firlak, E. Kok Yetimoglu, M. V. Kahraman (2018). UV Photocrosslinked Polymeric Fluorescent Sensor for Bisphenol A. Reactive and Functional Polymers, 132, 133. DOI: 10.1016/j.reactfunctpolym.2018.09.022

[13] A. A. S. Shah, M. Firlak, R. S. Berrow, N. R. Halcovitch, S. J. Baldock, B. M. Yousafzai, R. M. Hathout, J. G. Hardy (2018). Electrochemically Enhanced Drug Delivery Using Polypyrrole Films. Materials, 11, 1123. https://doi.org/10.3390/ma11071123

[12] M. Firlak, S. Cubuk, E. Kok Yetimoglu, M. V. Kahraman (2016). Recovery of Au(III) ions by Au(III)-imprinted hydrogel. Chemical Papers, 70(6), 757-768. DOI: 10.1515/chempap-2016-0019

[11] S. Cubuk, M. Firlak, N. Tasci, E. Kok Yetimoglu, M. V. Kahraman (2016). Phosphonic acid based polymeric fluorescent sensor for mercury (II) analysis. Sensors and Actuators B-Chemical, 224, 640-647. http://dx.doi.org/10.1016/j.snb.2015.10.056

[10] M. Ozyazıcı, M. Firlak, S. Tuncay Tanriverdi, S. Rencber, S. Y. Karavana, M. V. Kahraman (2015). Bioadhesive Gel and Hydrogel Systems for Buccal Delivery of Ketoprofen: Preparation and In vitro Evaluation Studies. American Journal of Drug Delivery and Therapeutics, 2(3), 78-91. http://www.imedpub.com/articles/bioadhesive-gel-and-hydrogel-systems-forbuccal-delivery-of-ketoprofen-preparationand-in-vitro-evaluation-studies.pdf

[9] M. Firlak, E. Kok Yetimoglu, M. V. Kahraman (2014). Adsorption of Au(III) ions from Aqueous Solutions by Thiol-Ene PhotoClick Hydrogels and Its Application to Electronic Waste and Geothermal Water. Journal of Water Process Engineering, 3(1), 105-116. http://dx.doi.org/10.1016/j.jwpe.2014.05.016

[8] Z. S. Can, M. Firlak, A. Kerc, S. Evcimen (2014). Evaluation of different wastewater treatment techniques in three WWTPs in Istanbul for the removal of selected EDCs in liquid phase. Environmental Monitoring and Assessment, 186(1), 525-539. http://link.springer.com/article/10.1007/s10661-013-3397-7

[7] M. Firlak, M. V. Kahraman, E. Kok Yetimoglu, (2014). Removal of Ag(I) from Aqueous Solutions by Thiol-Ene Based Hydrogel and Its Application to Radiograhic Films. Journal of Water, Air and Soil Pollution, 225(2), 1843-1853. http://link.springer.com/article/10.1007/s11270-013-1843-3

[6] M. Firlak, M. V. Kahraman, E. Kok Yetimoglu, B. Zeytuncu (2013). Adsorption of Ag (I) Ions from Aqueous Solutions Using Photocured Thiol-Ene Hydrogel. Separation Science and Technology, 48(18), 2860-2870. http://dx.doi.org/10.1080/01496395.2013.811692

[5] S. Cubuk, E. Kok Yetimoglu, M. V. Kahraman, P. Demirbilek, M. Firlak, (2013). Development of Photopolymerized Fluorescence Sensor for Glucose Analysis. Sensors and Actuators B: Chemical, 181(1), 187-193. http://dx.doi.org/10.1016/j.snb.2013.02.004

[4] M. Firlak, E. Kok Yetimoglu, M. V. Kahraman (2012). Preparation and Characterization of Photocured Thiol-ene Hydrogel: Adsorption of Au(III) Ions From Aqueous Solutions. Journal of Applied Polymer Science, 126(1), 322-332. http://onlinelibrary.wiley.com/doi/10.1002/app.36887/full

[3] E. Kok Yetimoglu, M. Firlak, M. V. Kahraman, S. Deniz (2011). Removal of Pb2+ and Cd2+ Ions from Aqueous Solutions Using Guanidine Modified Hydrogels. Polymers for Advanced Technologies, 22(5), 612-619. http://onlinelibrary.wiley.com/doi/10.1002/pat.1554/full

[2] M. Firlak, S. Cubuk, E. Kok Yetimoglu, M. V. Kahraman (2011). Uptake of Pb2+ Using N-Vinyl Imidazole Based Uniform Porous Hydrogels. Separation Science And Technology, 46(12), 1984-1993. http://dx.doi.org/10.1080/01496395.2011.579080

[1] M. Firlak, E. Kok Yetimoglu, M. V. Kahraman, N. Kayaman Apohan, S. Deniz (2009). Removal of Lead and Cadmium Ions from Aqueous Solutions Using Sulphur and Oxygen Donor Ligand Bearing Hydrogels. Separation Science and Technology, 45(1), 116-128. http://dx.doi.org/10.1080/01496390903256208

Invited Lectures and Presentations

[01] “Electrically Responsive Biomaterials as Potential Drug Delivery Systems” Melike Firlak, Sophie Au-Yong, Ashfaq Shah, Mark Ashton, John George Hardy, 4th International Congress on Biomaterials and Biosensors” (BIOMATSEN 2019), 12-18 May 2019, Mugla, Turkey.

International Oral and Poster Presentations (Proceedings)

[22] "Stimuli-responsive materials for controlled/triggered/sustained delivery of drugs or biologics" John G. Hardy, Melike Firlak, 9th International Drug Chemistry Congress 08-11 April 2021, Antalya, Turkey.

[21] “Stimuli-responsive biomaterials for drug delivery” Melike Firlak, Mark Ashton, Peter Goodwin, John G. Hardy, 6th Internationally attended Drug Chemistry Congress: Design, Synthesis, Production and Standardization of Drug Active Substances, 22-25 March 2018, Antalya, Turkey.

[20] “Electroactive Biomaterials as Potential Drug Delivery Systems” Melike Firlak, Ashfaq Shah, Nathan Halcovitch, Richard Mort, Ben Robinson, John George Hardy, 6th Internationally Attended Drug Chemistry Congress: Design, Synthesis, Production and Standardization of Drug Active Substances, 22-25 March 2018, Antalya, Turkey.

[19] “Towards Robust Electroactive Biomaterials” Melike Firlak, Ashfaq Shah, Nathan Halcovitch, Richard Mort, Ben J. Robinson, John G. Hardy, Materials Science Early Career Forum-Networking event and Symposium, 8 September 2017, London, UK.

[18] “Towards Robust Electroactive Biomaterials” Melike Firlak, Ashfaq Shah, Nathan Halcovitch, Richard Mort, Ben J. Robinson, John G. Hardy, Bioinspired Materials 2017 Conference, 31 August – 01 September 2017, Manchester, UK.

[17] “Towards Robust Electroactive Biomaterials” Melike Firlak, Ashfaq Shah, Nathan Halcovitch, Richard Mort, Ben J. Robinson, John G. Hardy, 13th International Conference on Materials Chemistry (MC13), 10-13 July 2017, Liverpool, UK.

[16] “Towards Robust Electroactive Biomaterials” Ashfaq Shah, Melike Firlak, Nathan Halcovitch, Richard Mort, Ben J. Robinson, John G. Hardy, RSC Materials Chemistry Division Poster Symposium, 25 November 2016, London, UK.

[15] “UV Cured Boronic Acid Based Fluorescence Sensor for the Determination of Glucose” S. Çubuk, E. Kok Yetimoğlu, M. V. Kahraman, S. Kenan, M. Firlak, ICHEAP-11: 11th International Conference on Chemical and Process Engineering, 32, 1663-1668., Doi: 10.3303/CET1332278, 2015.

[14] “Removal and Recovery of Silver Ions Using Thiol-ene Based Hydrogels” E. Kok Yetimoğlu, M. Firlak, M. V. Kahraman, The European Symposium of Photopolymer Science (ESPS2014), 2014.

[13] “Photocrosslinked Molecularly Imprinted Hydrogels for Adsorption Gold Ions in Aqueous Solution” S. Çubuk, M. Firlak, E. Kök Yetimoğlu, M. V. Kahraman, International Symposium on Advanced Polymeric Materials (ISAPM 2014) , 2014.

[12] “Polymeric Optical Fluorescence Sensor for the Determination of Gold (III)” S. Çubuk, E. Kök Yetimoğlu, M. V. Kahraman, S. Kenan, M. Firlak, 19th European Symposium on Polymer Spectroscopy (ESOPS19) 77th Prague Meeting on Macromolecules, 2013, Prague.

[11] “Ketoprofen Loaded Buccal Hydrogel Formulations: Preparation and In Vitro Evaluation” M.Özyazıcı, M. Firlak, S. Rençber, S. Y. Karavana, S. Tuncay Tanrıverdi, M. V. Kahraman, 16th International Pharmaceutical Technology Symposium , 10-12 September 2012 Antalya, Turkey.

[10] “Evaluation of Bioadhesive Buccal Hydrogel Formulations of Ketoprofen” Mine Özyazıcı, M. Firlak, S. Rençber, S. Y. Karavana, S. Tuncay Tanrıverdi, M. V. Kahraman, ISOPS-10, 10th International Symposium on Pharmaceutical Sciences, 26-29 June 2012, Ankara University, Ankara, Turkey.

[9] “Preparation and Characterization of P(Penta3MP4/PEG-DA/AAc) Thiol-Ene Based Hydrogels and Their Application on Adsorption of Gold Ions” Melike Firlak, M. Vezir Kahraman, Ece Kök Yetimoğlu, One-Day Workshop Recent Advances in Synthetic and Biological Gels, 21 September 2011, İstanbul Technical University, İstanbul-Turkey.

[8] “Monitoring and Oxidative Removal of EDCs in Istanbul Wastewater Treatment Plants” Zehra Semra Can, Aslıhan Kerç, Serkan Evcimen, Melike Firlak, 20th Ozone World Congress and 6th Ultraviolet World Congress, May 23-26, 2011, Paris, France.

[7] “Investigation of Endocrine Disrupting Compound Removal Efficiencies of Istanbul Wastewater Treatment Plants” S. Evcimen, M. Fırlak, A. Kerç, Z. S. Can, International Sustainable Water and Wastewater Management Symposium, Dedeman Otel, 26-28 October 2010, Konya, Turkey.

[6] “Removal Of Pb2+ Ions From Synthetic Wastewater Using A Novel N-Vinyl Imidazole Based Hydrogels” M. Firlak, S. Çubuk, E.Kök Yetimoğlu, M. V. Kahraman, International Sustainable Water and Wastewater Management Symposium, Dedeman Otel, 26-28 October 2010, Konya, Turkey.

[5] “Removal Of Lead And Cadmium Ions From Aqueous Solutions Using Sulphur Donor Ligand Bearing Hydrogels” Melike Firlak, M. Vezir Kahraman, Ece Kök Yetimoğlu, Sabahattin Deniz, 5th Black Sea Conference on Analytical Chemistry, 23-26 September 2009, Fatsa, Ordu, Turkey.

[4] “Recovery Of Lead And Cadmium Ions From Aqueous Solutions Using Poly (Guanidine Modified 2-Acrylamido-2-Methylpropane Sulfonic Acid /Acrylic Acid/ N-Vinylpyrrolidone/ 2-Hydroxyethyl Methacrylate)” Melike Firlak, M. Vezir Kahraman, Ece Kök Yetimoğlu, Sabahattin Deniz, 5th Black Sea Conference on Analytical Chemistry, 23-26 September 2009, Fatsa, Ordu, Turkey.

[3] “Screening Of Endocrine Disrupting Compounds In Paşaköy Municipal Wastewater Treatment Plant And Their Removal By Ozonation”, Melike Firlak, Zehra Semra CAN, Serkan EVCİMEN, Aslıhan KERÇ, 5th Black Sea Conference on Analytical Chemistry, 23-26 September 2009, Fatsa, Ordu, Turkey.

[2] “Pb 2+ Imprinted UV Cured Hydrogels” Melike Firlak, Ece Kök Yetimoğlu, M. Vezir Kahraman, Sabahattin Deniz. 8th Chemical Physics Congress, İstanbul Technical University, 24-25 April 2008 İstanbul-Turkey.

[1] “Molecular Imprinting Technology In Analytical Chemistry” Melike Firlak, Ece Kök Yetimoğlu, M.Vezir Kahraman, 8th Chemical Physics Congress, 8th Chemical Physics Congress, İstanbul Technical University, 24-25 April 2008 Istanbul-Turkey.


National Oral and Poster Presentations (Proceedings)


[16] “Biyoadezif Bukal Hidrojel Formülasyonlarının Hazırlanması” Melike Fırlak, Memet Vezir Kahraman, Sakine Tuncay Tanrıverdi, Mine Özyazıcı. 3. Ilaç Kimyası: Ilaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Kimyagerler Dernegi, Antalya, 20-22 Mart 2015. (Sözlü Sunum)

[15] “Glukoz Analizi Için UV Isınları Ile Sertlesebilen Polimer Esaslı Optik Sensör Gelistirilmesi” Soner Çubuk, Memet Vezir Kahraman, Ece Kök Yetimoğlu, Melike Fırlak. 7. Ulusal Analitik Kimya Kongresi, Kahramanmaraş Sütçü İmam Üniversitesi, Kahramanmaraş, 1-5 Eylül 2014. (Poster Sunumu)

[14] “Penta3MP4/PEGDA/HEMA Hidrojeli İle Au(III) İyonlarının Adsorpsiyonu ve Dönüşümlü Voltametri İle Tayini” Melike Fırlak, Seyfullah Madakbaş, Ece Kök Yetimoğlu, Memet Vezir Kahraman, IV. Fiziksel Kimya Kongresi, Pamukkale Üniversitesi, Denizli, 5-8 Haziran 2014. (Poster Sunumu)

[13] "Katı Faz Ekstraksiyonu ve GC/MS ile İstanbul’daki Evsel Atıksulardaki Endokrin Bozucu Maddelerin Taranması ve Giderimi" Melike Fırlak, Zehra Semra Can, Aslıhan Kerç, Serkan Evcimen, Türkiye'de Çevre Kirlenmesi Öncelikleri Sempozyumu VII, GYTE, İstanbul, 22-23 Kasım 2012. (Sözlü Sunum)

[12] “İyon Baskılı Hidrojellerle Au(III) İyonlarının Adsorpsiyonu” Melike Fırlak, Soner Çubuk, M. Vezir Kahraman, Ece Kök Yetimoğlu, III. Fiziksel Kimya Günleri, Balıkesir Üniversitesi, 12-15 Temmuz 2012, Balıkesir. (Poster Sunumu)

[11] “İmidazol Fonksiyonel Grubu İçeren Hidrojellerle Sulu Çözeltilerden Pb(II) İyonlarının Adsorpsiyonu” Ece Kök Yetimoğlu, Burcu Boztepe, Sabahattin Deniz, Mehmet Vezir Kahraman, Melike Fırlak, III. Fiziksel Kimya Günleri, Balıkesir Üniversitesi, 12-15 Temmuz 2012, Balıkesir. (Poster Sunumu)

[10] “NIPA, NVP Esaslı Hidrojeller ile Sulu Çözeltilerden Cd(II) İyonu Adsorpsiyonu” Ece Kök Yetimoğlu , Yeşim Kovankaya, Sabahattin Deniz, Mehmet Vezir Kahraman, Melike Fırlak, III. Fiziksel Kimya Günleri, Balıkesir Üniversitesi, 12-15 Temmuz 2012, Balıkesir. (Poster Sunumu)

[9] “P(Penta3MP4/PEGDA/AAc) Hidrojelleri ile Ag(I) İyonlarının Sulu Ortamdan Uzaklaştırılması” Melike Fırlak, Ece Kök Yetimoğlu, Memet Vezir Kahraman, II. Eser Analiz Çalıştayı, KTÜ, Trabzon, 27-30 Haziran 2012. (Poster Sunumu)

[8] “Bisfenol A’nın Sulu Ortamdan Hidrojellerle Adsorpsiyonu” Soner Çubuk, Ece Kök Yetimoğlu, Selin Beşler, Memet Vezir Kahraman, Melike Fırlak, (2012). II. Eser Analiz Çalıştayı, KTÜ, Trabzon, 27-30 Haziran 2012. (Poster Sunumu)

[7] “Ag(I) İyonlarının Tiyol-En Esaslı P(Penta3MP4/PEGDA/HEMA) Hidrojelleri İle Sulu Çözeltilerden Uzaklaştırılması” Melike Fırlak, Ece Kök Yetimoğlu, Memet Vezir Kahraman, I. Eser Analiz Çalıştayı, Pamukkale Üniversitesi, 22-25 Nisan 2010, Denizli. (Poster Sunumu)

[6] “UV Işınlarıyla Sertleşebilen Thiol-Ene Esaslı Hidrojellerle Au(III) İyonlarının Adsorpsiyonu” Melike Fırlak, Memet Vezir Kahraman, Ece Kök Yetimoğlu, I. Eser Analiz Çalıştayı, Pamukkale Üniversitesi, 22-25 Nisan 2010, Denizli. (Poster Sunumu)

[5] “Yeni Merkaptan Esaslı Hidrojellerle Au(III) İyonlarının Sulu Ortamdan Seçimli Adsorpsiyonun İncelenmesi” Melike Fırlak, M. Vezir Kahraman, Ece Kök Yetimoğlu, I. Eser Analiz Çalıştayı, Pamukkale Üniversitesi, 22-25 Nisan 2010, Denizli. (Poster Sunumu)

[4] “Tiyoüre, Üre ve Guanidin Modifiye 2-Akrilamido-2-Metilpropan Sulfonik Asit Esaslı Hidrojellerle Sulu Çözeltilerden Pb(II) ve Cd(II) İyonlarının Uzaklaştırılması” Melike Fırlak, M. Vezir Kahraman, Ece Kök Yetimoğlu, Sabahattin Deniz, 11. Ulusal Spektroskopi Kongresi, Gazi Üniversitesi, 23-26 Haziran 2009, Ankara. (Sözlü Sunumu)

[3] “Poli(NVP/AAc/HEMA/AMPSTU) Hidrojelleri İle Çözeltiden Altın Adsorpsiyonu” Ece Kök Yetimoğlu, Melike Fırlak, Sabahattin Deniz, M. Vezir Kahraman, 22. Ulusal Kimya Kongresi, Doğu Akdeniz Üniversitesi , 06-10 Ekim 2008 Gazi Magusa, Kıbrıs. (Poster Sunumu)

[2] “Sulfonamid Bazlı Hidrojellerle Agır Metallerin Adsorpsiyonu” Ece Kök Yetimoğlu, Melike Fırlak, Sabahattin Deniz, M. Vezir Kahraman, 22. Ulusal Kimya Kongresi, Doğu Akdeniz Üniversitesi , 06-10 Ekim 2008 Gazi Magusa, Kıbrıs. (Poster Sunumu)

[1] “UV Işınlarıyla Sertleştirilerek Hazırlanan Hidrojellerle Boyar Madde Absorpsiyonu.” E.K Yetimoğlu, M.V. Kahraman, Z.S Akdemir, M. Fırlak, N.K. Apohan. 10. Ulusal Spektroskopi Kongresi, İzmir Yüksek Teknoloji Enstitüsü, 04-07 Temmuz 2007, Urla-İzmir. (Poster Sunumu)

  • Third Cycle (Doctoral): Marmara Üniversitesi, Fen Bilimleri Enstitüsü, Analitik Kimya, 2013
  • Second Cycle (Master's): Marmara Üniversitesi, Fen Bilimleri Enstitüsü, Analitik Kimya, 2008
  • First Cycle (Undergraduate): Marmara Üniversitesi, Fen Edebiyat Fakültesi, Kimya, 2006
Postdoctoral Research Fellow, Lancaster University, Lancaster, United Kingdom (June 2016-June 2018)


Awards and Honours

2017 MCD Networking Prize, Royal Society of Chemistry.

2016 Newton İnternational Fellowship, “Electroactive Hydrogels for Chronotherapeutic Drug Delivery” Royal Society.

2010 Novartis Science Awards, 3rd Prize of Pharmaceutical Technology Branch.


Other Professional Experience

Nov 2016 - Present Member Royal Society of Chemistry
May 2009 – Present Member Turkey Chemist’s Society
Jan 2014 – Jan 2016 Executive Board Member Turkey Chemist’s Society
Head of Publication Board Turkey Chemist’s Society
Jan 2012 – Dec 2015 Executive Board Member Turkey Chemist’s Society
Accounter Turkey Chemist’s Society
Head of Social Event Board Turkey Chemist’s Society
Jan 2011 – Dec 2011 Executive Board Member Turkey Chemist’s Society
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