gtu_logo

Doç. Dr. Hülya Akdemir
Moleküler Biyoloji ve Genetik

Hülya Akdemir
Telefon
(262) 605 25 54
E-Posta
hakdemir@gtu.edu.tr
Ofis
C2 Blok, 205
Çalışma alanları
Metabolizma mühendisliği, Bitki metabolitlerinin mikrobiyal üretimi, Transgenik bitkiler, Bitkilerde gen ekspresyonu, Doku kültürü

Indexed Publications (SCI - SCI Expanded)

  1. Akdemir H, Liu Yuxin, Zhuang Lei, Zhang Haoran, Koffas Mattheos AG (2022). Utilization of microbial co-cultures for converting mixed substrates to valuable bioproducts. Current Opinion in Microbiology 68:102157.
  2. Akdemir H, Seven Merve, Derman Ümit Cem, Harvey Andrew John (2022). In silico analysis of XTH gene family from barley (Hordeum vulgare L.) and their comparative expression analysis during germination. Turk J Bot, 46, 92-108
  3. Akdemir H (2021). Evaluation of transcription factor and aquaporin gene expressions in response to Al2O3 and ZnO nanoparticles during barley germination. Plant Physiology and Biochemistry, 166
  4. Seven M, Akdemir H 2020. DOF, MYB and TCP transcription factors: Their possible roles on barley germination and seedling establishment. Gene Expression Patterns 37:119116
  5. Akdemir H, Silva A, Zha J, Zagorevski D, Koffas MA2019. Production of pyranoanthocyanins using Escherichia coli co-cultures. Journal of Metabolic Engineering, 55:290-298
  6. Şah I,Akdemir H,Kaya E, Akkaya Ö, Ozden Çiftçi Y.2019. The association of fraser photinia and its beneficial bacterium (PGB_invit) provided in vitro storage without subculture. Plant Cell, Tissue and Organ Culture (PCTOC) 136:605–615
  7. Akdemir H, Suzerer V, Onay A, Tilkat E, Ozden Çiftçi Y2016. Detection of variation in long-term micropropagated mature pistachio via DNA-based molecular markers. Applied Biochemistry and Biotechnology, 180:1301-1312
  8. Chu MY, Quinonero C, Akdemir H, Alburquerque N, Pedreno MA, Burgos L2016. Agrobacterium-mediated transformation of Vitis cv. Monastrell suspension-cultured cells. Biotechnology Progress, 32:725–734
  9. Koç İ, Akdemir H, Onay A, Ozden Çiftçi Y2014. Cold-induced genetic instability in micropropagated Pistacia lentiscus L. plantlets. Acta Physiologiae Plantarum, 36(9):2373-2384
  10. Akdemir H, Suzerer V, Onay A, Tilkat E, Ersali Y, Ozden Çiftçi Y.2014. Micropropagation of the pistachio and its rootstocks by temporary immersion system. Plant Cell Tissue and Organ Culture, 117:65-76
  11. Akdemir H, Suzerer V, Tilkat E, Yildirim H, Onay A, Ozden Çiftçi Y.2013. In vitro conservation and cryopreservation of mature pistachio (Pistacia vera L.) germplasm. Journal of Plant Biochemistry and Biotechnology, 22(1):43-51
  12. Yildirim H, Akdemir H, Suzerer V, Ozden Y, Onay A.2013. In vitro micrografting of the almond cultivars 'Texas', 'Ferrastar' and 'Nonpareil'. Biotechnology and Biotechnology Equipment, 27(1):3493-3501
  13. Yildirim H, Onay A, Suzerer V, Tilkat E, Ozden Tokatlı Y, Akdemir H2010. Micrografting of almond (Prunus dulcis Mill.) cultivars “Ferragnes” and “Ferraduel”. Scientia Horticulturae, 125(3):361-367
  14. Ozden-Tokatli Y,Akdemir H, Tilkat E, Onay A.2010. Current status and conservation of Pistacia germplasm. Biotechnology Advances, 28:130-141
  15. Ozden Tokatli Y and Akdemir H.2010. Cryopreservation of fraser photinia (Photinia x fraseri dress.) via vitrification-based one-step freezing techniques. CryoLetters, 31(1):40-49
  16. Akdemir H, Kaya E, Ozden Y2010. In vitro proliferation and minimum growth storage of fraser photinia: Influences of different medium, sugar combinations and culture vessels. Scientia Horticulturae, 126:268-275

Books
1.Cryopreservation in Eukaryotes (2016). Francisco M. Jimenez, Hülya Akdemir (Eds.), 2016. InTech Publishing, ISBN 978-953-51-2779-6.

Book Chapters

1.ONAY AHMET,ÖZDEN ÇIFTÇI YELDA,Akdemir H,SÜZERER VEYSEL,TILKAT ENGIN, 2020 Biotechnology of Fruit and Nut Crops:Pistacia vera pistachio, Editör:Richard Litz, E. CABI,ISBN:978-1-78064-827-9

2.Akdemir H,YILDIRIM HAKAN,EKINCI REMZI,ONAY AHMET 2020 Kenevir (Cannabis Sativa L.):Kenevirin Genetigi ve Islahı, Editör:Ahmet ONAY, Hakan YILDIRIM, Remzi EKINCI, PALME YAYINEVI, ISBN:978-605-282-491-7

3.Akdemir H, Gago J, Gallego PP, Ozden Çiftçi Y. 2012. Recent advances in fruit species transformation. In: Transgenic Plants-Advances and Limitations (Ed.Y.Ozden Çiftçi) pp. 27-62 ISBN: 978-953-307-953-0.

4.Tilkat E, Ozden-Tokatli Y, Akdemir H, Onay A, Ayaz Tilkat E. 2012. Novel Methods in Micropropagation of Pistachio, (Eds. Ashraf M, Öztürk M, Ahmad MSA, Aksoy A). In: Springer, Crop Production for Agricultural Improvement. pp. 379-393.

5.Akdemir H, Onay A. 2017. Biotechnological approaches for conservation of the Genus Pistacia. (Eds. M.R. Ahuja, S.Mohan Jain) In: Springer, Biodiversity and Conservation of Woody Plants pp 221-244

Peer-reviewed Articles

1.Zha J, Koffas MAG, Akdemir H. 2018. The potential for E.coli to color cosmetics. Cosmetics and Toiletries, 133 (7):36-42.

2.Tilkat E, Süzerer V, Akdemir H,Ayaz Tilkat E, Özden Çiftçi Y, Onay A. 2013. A rapid and effective protocol for surface sterilization and in vitro culture initiation of adult male pistachio (Pistacia vera L. cv. "Atlı") Acad. J. Sci. Res. 1(8):134-141

Conference Proceedings in Journals

1. Tilkat E, Suzerer V, Ersali Y, Hoşer A, Gül C, Kilinç FM, Ayaz Tilkat E, Akdemir H, Ozden Çiftçi Y, Onay A. 2014. Mass shoot proliferation of Pistacia khinjuk Stocks using temporary immersion bioreactor system (TIS). Acta Horticulturae, 1028:145-151.

2. Kilinç FM, Suzerer V, Ozden Çiftçi Y, Koc I, Akdemir H, Yildirim H, Tilkat E, Onay A. 2014. Improved shoot multiplication of lentisk (Pistacia lentiscus L.) in vitro using different carbohydrates and medium strengths. Acta Horticulturae, 1028:153-160.

3. Akdemir H, Tilkat E, Yıldırım H, Onay A, Ozden-Tokatlı Y. 2011. Development of Synthetic Seed Technology for the Conservation of Pistachio Germplasm Acta Horticulturae, 912:581-586.

4. Tilkat E, Akdemir H, Yildirim H, Ozden Tokatlı Y, Suzerer V., Onay A. 2011. Plant Production Through Adventive Organogenesis of Mature Pistachio, Pistacia vera L. Cultivars ‘Atlı’ and ‘Siirt’. Acta Horticulturae, 912:567-574.

5. Onay A, Suzerer V, Akdemir H, Yildirim H, Ozden Tokatlı Y, Tilkat E. 2011. Micropropagation of Pistachio: "The Wave of the Future?". Acta Horticulturae, 912:553-560.

6. Ozden-Tokatlı Y, Akdemir H, Kaya E, Tilkat E, Yildirim H, Onay A. 2011. In vitro Conservation and Cryopreservation of Turkish Pistachio Germplasm. Acta Horticulturae, 912:545-552.

7. Akdemir H and Ozden-Tokatli Y. 2011. Long-term storage of fraser photinia shoot tips via conventional and droplet vitrification techniques. Acta Horticulturae, 908:297-302.

8. Onay A, Suzerer V, Akdemir H, Yildirim H, Ozden Tokatlı Y, Tilkat E. 2011. Somatic Embryogenesis in Pistachios. Acta Horticulturae, 912:587-592.

9. Ozden-Tokatli Y, Ozudogru A, Akdemir H, De Carlo A, Gumusel F. 2009. Application of Cryopreservation for Pistachio Germplasm Conservation. Acta Horticulturae, 839:245-251.

Conferences with Journal Abstracts

  1. Akdemir H(2021). Production of complex anthocyanins using recombinant microorganisms. ICOMNAS – Uluslararası Multidisipliner Doğa Bilimleri Kongresi
  2. Akdemir H (2021). Efficient bioconversion of hydroxycinnamic acids to their decarboxylation products in microorganisms. ISMSIT 2021 5th International Symposium on Multidisciplinary Studies and Innovative Technologies, 58-58.
  3. Akdemir Koç H,Zha J, Silva A, Koffas M. 2018. Production of pyranoanthocyanins in E.coli coculture. SEED 2018 Synthetic Biology: Engineering, Evolution and Design, p.15, June 3-7 2018. Scottsdale, Arizona, USA
  4. Akdemir Koç H, Wang R, Koffas MAG. 2018. Production of prenylated flavanoids and anthocyanins. Metabolic Engineering 12, June 24th-28th 2018, p.116, Munich, Germany
  5. Çalar N,Yıldırım H, Akdemir Koç H, İlikçioğlu, Onay A. 2018. Micropropagation of Pictacia hybrids. International Symposium Ecology 2018. 19-23 June 2018, p.1028, Kastamonu, Turkey
  6. Onay A,Akdemir Koç H, Süzerer V, Kılınç FM, Yavuz MA, Tilkat E.2017. Antepfıstığı, Pistacia vera L.'nin korunması için biyoteknolojik yaklaşımlar. XIII. Congress of Ecology and Environment with International Participition p.745. 12-15 September 2017, Edirne, Turkey (in Turkish)
  7. Merve Seven, Ü. Cem Derman, N. Rüyam Fettahoğlu, Andrew J. Harvey,Hülya Akdemir. 2016. Gene expression profiles of xyloglucan endotransglycosylases (XTH) during barley germination. Plant Genes and “Omics”: Technology Development, p.18, February, 11-12 2016, Vienna, Austria
  8. Yelda Özden Çiftçi,Hülya Akdemir, Veysel Süzerer. 2015. Mass Propagation of Plants via Bioreactors. September, 2015, International Workshop on Green Biotechnology, p 35, Darıca, Kocaeli, Turkey
  9. Chu MY, Ouinonero C, Akdemir H, Pedreno MA, Burgos L. 2014. Transformacion mediada por Agrobacterium de cultivos celulares de vid. 11-13 June 2014. Cartagena, Murcia (in Spanish)
  10. Tuğçe Akbulak, Veysel Süzerer,Hülya Akdemir, Ergun Kaya, Yelda Özden Çiftçi. Alev ağacı (Photinia fraseri Dress.) Süs Bitkisinin Mikroçoğaltımında Sıvı Kültür ve Geçici Daldırma Biyoreaktör Sistemlerinin Kullanımı. 22.Ulusal Biyoloji Kongresi, s. 870, Eskişehir, 23-27 Haziran 2014 (in Turkish)
  11. Hülya Akdemir, Veysel Süzerer, Engin Tilkat, Ahmet Onay, Yelda Özden Çiftçi. Antepfıstığının Damlacık-Vitrifikasyon Tek Aşamalı Dondurma Yöntemi ile Kriyoprezervasyonu. 22.Ulusal Biyoloji Kongresi, s 154, Eskişehir, 23-27 Haziran 2014 (in Turkish)
  12. Engin Tilkat, Ahmet Onay, Yusuf Ersalı, Zeynep Ekinci, Ayşe Hoşer, Alevcan Kaplan, Hakan Yıldırım, Fatih Mehmet Kılınç, Veysel Süzerer,Hülya Akdemir, Yelda Özden Çiftçi, Ahu Altınkut Uncuoğlu, Ömer Faruk Akdemir. Olgun Buttum (Pistacia khinjuk Stocks) Ağaçlarından Rejenere Edilen Aksenik Sürgünlerin Geçici Daldırma Bioreaktör Sistemi (TIS) Kullanarak Kitlesel Çoğaltımı. 22.Ulusal Biyoloji Kongresi, s 795, Eskişehir, 23-27 Haziran 2014 (in Turkish)
  13. Veysel Süzerer, Ahmet Onay, Fatih Mehmet Kılınç, Yelda Özden Çiftçi, Ahu Altınkut Uncuoğlu, Ömer Faruk Akdemir, Engin Tilkat, Nazan Çalar,Hülya Akdemir. 2014. In vitro micrografting of Mastic Tree, Pistacia lentiscus. In vitro Biology Meeting of the SIVB, Georgia, Savannah, USA p.63
  14. Veysel Süzerer, Özge Karakaş Metin, İbrahim Koç, Ahmet Onay, Fatih Mehmet Kılınç, Yelda Özden Çiftçi, Ahu Altınkut Uncuoğlu, Ömer Faruk Akdemir, Engin Tilkat, Nazan Çalar,Hülya Akdemir. 2014. Assessment of Clonal Fidelity Between Selected Lentisk Genotypes (Pistacia lentiscus L.) by IRAP and Florescentbased AFLPJune 2014. In vitro Biology Meeting of the SIVB, p.63-64, Georgia, Savannah, USA
  15. Hamit Ekinci, Ceyhun Öztürk,Hülya Akdemir, Veysel Süzerer, Yelda Özden Çiftçi, 2014. Assessment of Genetic Stability of Cryopreserved Fraser Photinia via Retrotransposon-Based Molecular Marker. June 2014, Biology Meeting of the SIVB, p. 52, Savannah, Georgia, USA
  16. Hülya Akdemir, Veysel Süzerer, Engin Tilkat, Ahmet Onay, Veysel Süzerer. 2014. Genetic Instability of Long-Term Micropropagated Mature Pistachio. June 2014, In vitro Biology Meeting of the SIVB, p 34, Savannah, Georgia, USA
  17. Hülya Akdemir, Yelda Özden Çiftçi and Veysel Süzerer, 2013. Assessment of different immersion frequency and period on pistachio micropropagation in temporary immersion system. February 2013, 2nd World Biotechnology Congress, pp 103-104, DubaiUAE
  18. Veysel Süzerer,Hülya Akdemir, Yelda Özden Çiftçi. 2013. Usage of Synseed Technology for the Medium Term Conservation of Female Pistachio Cultivar. February 2013, 2nd World Biotechnology Congress, pp 110-111, Dubai, UAE
  19. Engin Tilkat, Yusuf Ersalı, Ayşe Hoşer, Veysel Süzerer, Emine Ayaz Tilkat,Hülya Akdemir, Yelda Özden Çiftçi, Hakan Yıldırım, Ahmet Onay. 2012. Antepfıstığı anaçlarının (Pistacia terebinthus, Pistacia vera, Pistacia khinjuk ve Pistacia paleastina) in vitro mikroçoğaltılması. 21.Ulusal Biyoloji Kongresi, ss 714-715, İzmir, Eylül 2012 (in Turkish)
  20. Ahmet Onay, Hakan Yıldırım, Yelda Özden Çiftçi, Engin Tilkat, Mahir Binici, Nazan Çalar, Fatih Mehmet Kılınç,Hülya Akdemir, Ömer Faruk Akdemir, Veysel Süzerer, İbrahim Koç. 2012. Bitkilerin in vitro mikroçoğaltım teknikleri, 21.Ulusal Biyoloji Kongresi, ss 152-153, İzmir, Eylül 2012 (in Turkish)
  21. Veysel Süzerer,Hülya Akdemir, Hakan Yıldırım, Ahmet Onay, Yelda Özden Çiftçi, 2012. Assesment of genetic stability of in vitro micrografted and micropropagated almond cv. Texas. 2012 In vitro Biology Meeting of the SIVB, pp 77-78, Seattle, Washington
  22. Doğa Gümüşel,Hülya Akdemir, Veysel Süzerer, Yelda Özden Çiftçi, 2012. Influences of different medium compositions and cytokinins on micropropagation of fraser photinia. 2012. In vitro Biology Meeting of the SIVB, pp 76-77, Seattle, Washington
  23. Hülya Akdemir, Hakan Yıldırım, Engin Tilkat, Ahmet Onay, Yelda Özden Çiftçi, 2012. Prevention of shoot tip necrosis responses in in vitro-proliferated mature pistachio plantlets. 2012. In vitro Biology Meeting of the SIVB, Seattle, Washington
  24. Kaya E.,Akdemir H., Ozudogru E.A., Ozden Y. 2011. “In vitro Propagation of Turkish olive cultivar “Edremit yaglık” via Temporary Immersion Bioreactor Systems” 13th World Congress of the IABP and 2010 In vitro Biology Meeting of the SIVB, Raleight, North Carolina
  25. Ahmet Onay, Hakan Yildirim, Yelda Ozden Tokatli,Hulya Akdemir, Veysel Suzerer 2011. Plant tissue culture techniques — Tools in plant micropropagation. Current Opinion in Biotechnology Volume 22, Supplement 1, September 2011, Page S130 European Biotechnology Congress Abstract
  26. İşsever-Öztürk S,Akdemir H,Akbulut N, Gümüşel F. 2008. Purification of recombinant penicillin acylases originated from the wild type or altered expression casettes and characterization of the enzyme. The International Enzyme Engineering Symposium, p.62, Kuşadası, Turkey
  27. Ozudogru EA, Ozden-Tokatli Y, Kaya E,Akdemir H, Benelli C, Gumusel F, Lambardi M. 2007. Domates bitkisinin in vitro çoğaltımı ve vitrifikasyon / tek aşamalı dondurma tekniği ile kriyoprezervasyonu. XV. Ulusal Biyoteknoloji Kongresi, pp. 13-14. Antalya (in Turkish)
  28. Ozden-Tokatli Y, Ozudogru EA, Kaya E, Akdemir H, Benelli C, Gumusel F, Lambardi M. 2007. Geçici daldırma biyoreaktör sisteminin bitki doku kültürü çalışmalarında kullanımı. XV. Ulusal Biyoteknoloji Kongresi, pp. 148-150.Antalya

Translated Book Chapters
1. Yelda Özden Çiftçi, Hülya Akdemir. 2012. Book Title: Botanik: Bitki Biyolojisine Giriş. Part 2: Bitki Fizyolojisi ve Gelişme Bölüm 15: Metabolizma ve Gelişimin Genetik Temelleri ve Genler. Çeviri Editörleri: Prof. Dr. Hasan Çetin Özen, Prof. Dr. Murat Biricik (Botany: An Introduction to Plant Biology; Ed. James D. Mauseth). Nobel Kitapevi, Ankara (in Turkish).

National articles

1.Akdemir H (2021)Nanoparticles-Mediated Changes on Gene Expressions and Physiological Parameters of Capsicum annuum L.. Experimed, 11

2.Akdemir H,Seven M, Kalay Ş, Culha M, Harvey AJ. 2019. Farklı nanotüplerin arpa çimlenmesi üzerindeki etkileri.Experimed 9(2):53-59

3.Akdemir H, Akbulak T, Süzerer V, Kayıhan D, Koç İ, Özden Çiftçi Y. 2016. Farklı sitokinin ve şeker türlerinin alev ağacı bitkisinin in vitro çoğaltımına olan etkileri. Anadolu Tarım Bilimleri Dergisi 31(2):248-255

4.Özden Çiftçi Y,Akdemir H, Süzerer V, Tilkat E, Onay A. 2012. Olgun Antepfıstığı Mikrosürgünlerinin Orta Süreli in vitro Saklanması, Uluslararası katılımlı Bilim ve Kültür Sempozyumu, ss 395-402, Batman Üniversitesi-Batman, Nisan 2012 (in Turkish).

5.Onay A,Yıldırım H, Pirinç V, Tilkat E, Özden Çiftçi Y, Akdemir H, Süzerer V, Çalar N, Binici M, Akdemir ÖF, Kılınç FM. 2012. Bitkilerin biyoteknolojik yöntemlerle ticari çoğaltımı, mevcut ve gelecekteki durum. Uluslararası katılımlı Bilim ve Kültür Sempozyumu, ss 11-28, Batman Üniversitesi-Batman, Nisan 2012 (in Turkish).

6.Kaya E,Akdemir H, Özden Y. 2010. Recent Biotechnological Advances in Olive Micropropagation and Conservation. Zeytin Bilimi Dergisi No: 2, p: 85-94 (in Turkish).

6.Özden Y, Özüdoğru EA, Kaya E,Akdemir H. 2010. Improvement of In vitro Shoot Proliferation of Olive (Olea europaea) via Temporary Immersion Bioreactor Systems (TIS). Zeytin Bilimi Dergisi No: 1, p:1-7 (in Turkish).

Projects
1. Investigation of gene expressions of xyloglucan endotransglycosylases (XTH) during barley (Hordeum vulgare L.) germination [TUBITAK of Turkey, n° 214Z248, 2015-2016, Principal investigator]

2. Development of biotechnological techniques for the propagation (via temporary immersion bioreactor systems), cryopreservation and identification of genetic fidelity of propagated/cryopreserved plantlets from juvenile and mature ‘Siirt’ and mature ‘Atlı’ varieties of pistachio (Pistacia vera L.) [TUBITAK of Turkey, n° 209T030, 2010-2013, Researcher]

3. Cryopreservation and assessment of genetic fidelity of long-term in vitro proliferated and conserved mature pistachio clones via RAPD/RAF molecular marker [GYTE Scientific Research Committee, n° 2009-A-10, 2009-2010, Researcher].

4. In vitro propagation and long term conservation of Thymus vulgaris germplasm [GYTE Scientific Research Committee, n° 2008-2009, Researcher].

5. In vitro proliferation of pistachio and its rootstocks by using temporary immersion bioreactor systems [GYTE Scientific Research Committee, n°2008-A-14, 2008-2009, Researcher].

6. Identification of olive cultivars via molecular characterization (RAPD; AFLP; SSR; ISSR) and micropropagation of identified cultivars by temporary immersion bioreactor systems. [GYTE Scientific Research Committee, 2007-2008, Researcher].

Awards
Plant Biotechnology Post-Doctoral Scientist Oral Presentation Competition (Third place). Joint Meeting of the Society for In Vitro Biology and the Society for Cryobiology, Savannah, Georgia, May 31 – June 4, 2014.

  • Doktora: Gebze Yüksek Teknoloji Enstitüsü, Fen Bilimleri Enstitüsü, Moleküler Biyoloji ve Genetik Anabilim Dalı (2013)
  • Yüksek lisans: Gebze Yüksek Teknoloji Enstitüsü, Fen Bilimleri Enstitüsü, Biyoloji Anabilim Dalı (2007)
  • Lisans: İstanbul Üniversitesi, Fen Fakültesi, Biyoloji Bölümü (2002)
Postdoc (2017-2018): Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

Postdoc (2013-2015): Genetik ve Biyomühendislik Bölümü, Yeditepe Üniversitesi, İstanbul, Türkiye