gtu_logo

Prof. Dr. Tamer YAĞCI
Moleküler Biyoloji ve Genetik

Tamer YAĞCI
Telefon
(262) 605 25 73
E-Posta
tyagci@gtu.edu.tr
Ofis
C2 Blok, 224
Çalışma alanları
Hepatokarsinogenezin moleküler biyolojisi ve genetiği Hibridoma teknolojisi uygulamaları: Kanserde moleküler belirteç ve tedavi hedeflerine yönelik monoklonal antikorların geliştirilmesi

1. Ceran C, Cokol M, Cingoz S, Tasan I, Ozturk M, Yagci T. Novel anti-HER2 monoclonal antibodies: synergy and antagonism with tumor necrosis factor-α. BMC Cancer 12(1):450 (2012).

2. Buyuktanir O, Yagci T, Findik A, Yildirim T, Yurdusev N. Generation of Mouse Hybridomas Secreting Anti-Salmonella Enteritidis Antibodies and Their Preliminary Characterization. KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI 17 (4): 667-670 (2011).

3. Acun T, Oztas E, Yagci T, Yakicier MC. SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. BMC Cancer 11:223 (2011).

4. Oztas E, Avci ME, Ozcan A, Sayan AE, Tulchinsky E, Yagci T. Novel monoclonal antibodies detect Smad-Interacting Protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays. Exp Mol Pathol 89 (2): 182–189 (2010).

5. Sayan AE, Griffiths TR, Pal R, Browne GJ, Ruddick A, Yagci T, Edwards R, Mayer NJ, Qazi H, Goyal S, Fernandez S, Straatman K, Jones GD, Bowman KJ, Colquhoun A, Mellon JK, Kriajevska M, Tulchinsky E. SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer. Proc Natl Acad Sci U S A 106 (35): 14884–14889 (2009).

6. Avci ME, Konu O, Yagci T. Quantification of SLIT-ROBO transcripts in hepatocellular carcinoma reveals two groups of genes with coordinate expression. BMC Cancer 29;8(1):392 (2008).

7. Yagci A, Yagci T, Sener B, Suziki Y, Ahmed K. Sulfatide mediates attachment of Pseudomonas aeruginosa to human pharyngeal epithelial cells. New Microbiol. 30 (2): 167–171 (2007).

8. Celikkaya H, Ciraci C, Oztas E, Avci ME, Ozturk M, Yagci T. Immunization with UV-induced apoptotic cells generates monoclonal antibodies against proteins differentially expressed in hepatocellular carcinoma cell lines. Hybridoma (Larchmt). 26 (2): 55–61 (2007).

9. Ozturk N, Erdal E, Mumcuoglu M, Akcali KC, Yalcin O, Senturk S, Arslan-Ergul A, Gur B, Yulug I, Cetin-Atalay R, Yakicier C, Yagci T, Tez M, Ozturk M. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells. Proc Natl Acad Sci U S A. 103 (7): 2178–83 (2006)

10. Yolcu, E., Sayan, B.S., Yagci, T., Cetin-Atalay, R., Soussi, T., Yurdusev, N. and Ozturk, M. A monoclonal antibody against DNA binding helix of p53 protein. Oncogene 20 (11): 1398–1401. (2001).

11. Wang, Q., Desseigne, F., Lasset, C., Saurin, J.C., Navarro, C., Yagci, T., Keser, I., Bagci, H., Luleci, G., Gelen, T., Chayvialle, J.A. and Ozturk, M. Germline hMSH2 and hMLH1 gene mutations in incomplete HNPCC families. Int. J. Cancer. 73 (6): 831–836 (1997).

12. Sahraoui, Y., Perraki, M., Theodoropoulou, M., Allouche, M., Tsapis, A., Ammar, A., Clemenceau, C., Bokogiorgou, S., Yacci, T., Katrinakis, G., Jasmin C., Georgoulias, V. Autocrine IL-2 dependent growth of a newly established CD3+, CD16-, CD56+, CD57+, J(H)-, TCRbeta-, TCRgamma- leukemia cell line (NOI-90). Leukemia 11 (2): 245–252 (1997).

13. Yagci, T., Göksel, S., Dogan, O., Ozturk, M. and Yurdusev, N. Genomic instability in colorectal cancer in Turkey. Int. J. Cancer 68 (3): 291–294 (1996).

14. Kebudi, R., Ayan, I., Darendeliler, E., Ağaoğlu, L., Pişkin, S., Yagci, T., Ekmekçioğlu, S., Yılmaz, G., Bilge, N.. Immunological status in children with brain tumors and the effect of therapy. J. Neuro-Oncol. 24 (3): 219–227 (1995).

  • Doktora: İstanbul Üniversitesi Onkoloji Enstitüsü
  • Yüksek lisans: İstanbul Üniversitesi, İstanbul Tıp Fakültesi
  • Lisans: