Arş. Gör. Kübra AKBULUT
Biyomühendislik

Kübra AKBULUT
Telefon
(262) 605 20 80
E-Posta
klacin@gtu.edu.tr
Web sayfası
linkedin.com/in/kübra-laçın-akbulut-661281336
Ofis
, Biyomühendislik Binası, BYM002
Ofis saatleri
 
Çalışma alanları
Biyoteknoloji, Fermentasyon Teknolojileri, Biyoproses Dizayn, Biyokatalizörler, Kimyasal ve Mikrobiyal Nanopartikül Sentezi, Optimizasyonu, Karakterizasyonu

-Erdem, A., Akbulut, K., Türker, M., Binay, B. 2025."Recombinant Expression and Bioprocess Optimization of Priestia megaterium α-Amylase and Its Impact on Dough Fermentation Efficiency", Chemistry and Biodiversity, e00866 .

Akbulut, K., Taranacı, S., Özkök, S., Varan, N., Yildirim, D., Binay, B. (2025). Heterologous expression of calcium-independent mesophilic α-amylase from Priestia megaterium: Immobilization on genipin-modified multi-walled carbon nanotubes and silica supports to enhance thermostability and catalytic activity. Bioorganic Chemistry, 155, 108151.

-Caloglu, B., Lacin, K., Binay, B., Hung, Y. T. 2023. "Microbial Enzymes For Wastewater Treatment"; In The Biotechnology, Agricultural And Food Industries, Ed: Hung, Y-T., Wang, L. K., and Wang, M-S., Springer, 27 (3), pp:65-132.

-Laçın, K., Çaloğlu, B., Binay, B. 2023. “Anaerobic digestion methods for the production of fuels”. Ed.K. P. Shadangi, P. K. Sarangi, K. Mohanty, I. Deniz, A. R. K. Gollakota (First Edition), Bioenergy Engineering (C. 551, ss 202-229). Elsevier.

–Ergun B.G., Lacin, K., Caloglu, B., Binay, B., 2023 “Second Genartion Pichia pastoris Strains and Bioprocess Designs”, Biotechnology for Biofuels and Bioproduct, 15(1), 150.

KONFERANS SUNUMLARI

o Akbulut, K., Binay, B. (2025)."Sonochemical synthesis of bimetallic hybrid nanoflowers with enhanced amylase catalytic activity". 49th FEBS Congress, 5-9 July, Istanbul (Poster)

o Birdal, B., Bahçivan, B., Laçın, K., Binay,B. (2024). "Covalent Immobilization of Bacterial α-Amylase Onto Activated Chitosan Beads: Optimization by Using Box-Behnken Design and Characterization" 5th International Enzyme and Bioprocess Days 27-29 Agust İzmir (Oral Presentation)

o Taranacı S., Özkök., S.,Laçın, K., Binay, B. (2023). “Expression and Characterization of a-Amylase from Priestia megaterium in Escherichia coli Expression Systems”.5th International Enzyme and Bioprocess Days 27-29 Agust İzmir (Poster)

o Birdal, B., Bahçivan, B.,Laçın, K., Binay,B. (2024). "Covalent Immobilization of Bacterial α-Amylase Onto Natural Organic Polymer and Optimization by Using Box- Behnken Design " 1st International Congress on Biotech Solutions for Sustainability May 7-10th Kocaeli (Poster)

oLaçın, K., Binay, B. (2023). “Searching for heterologous expression efficiency of a-amylase in Komagataella phafii using pAOX1 and pGAP promoters in 3L lab-scale bioreactor.” 4th International Enzyme and Bioprocess Days 07-09 September Kars (Poster)

o Erdem, A., Laçın, K., Binay, B., Türker, M. (2023). “Optimization and scale-up of a-amylase production by recombinant Pichia pastoris”. 4th International Enzyme & Bioprocess Days & 07-09 September Kars (Poster).

o Lacin, K., Vazquez Pereira,E., Valero Barranco, F., Binay, B. “Comparison of Bacillus aryabhattai α-amylase expression and secretion in Pichia pastoris by constitutive glyceraldehyde-3-phosphate dehydrogenase and inducible alcoholoxidase I promoters” , 3rd International Enzyme and Bioprocess Days, Tokat, 9-11 September 2022 (Oral Presentation)

o Lacin, K., Durmaz Sam, S., Mataracı Kara, E., Ozbek Celik, B. “Green Synthesis, Characterization and Potential Toxicity of Silver-Curcumin Nanocomposites”, 6th International Congress on Applied Biological Science, 8-9 Dec.2021, (Oral Presentation)

o Lacin, K., Durmaz Sam, S., Sayar, A. A. “Microbial synthesis of silver nanoparticles”, 2nd International Eurasian Conference on Science, Engineering and Technology 7-9 October 2020, (Poster Presentation)

o Lacin, K., Durmaz Sam, S., Sayar, A. A.“ Quantitative Detection of Curcuminoids by HPLC”, 2nd International Eurasian Conference on Biological and Chemical Sciences, 28-29 June 2019, (Oral Presentation)

Ders Kodu Ders Adı

o Immobilization of Industrially important enzymes, Doktora, Devam ediyor

Danışman: Prof. Dr. Barış BİNAY

o Microbial Synthesis of Silver Nanoparticles, Yüksek Lisans

Danışman: Prof. Dr. Ahmet Alp SAYAR

II. Danışman: Dr. Selçen DURMAZ ŞAM

o Bioprocess Design of Algal Biorefinery using Poultry Waste as Feed Stock, Lisans

Danışman: Prof. Dr. Dilek KAZAN

  • Doktora: Gebze Teknik Üniversitesi/Biyoteknoloji Enstitüsü (2021-)

    Scholor (COST_STSM)- (April-July 2022)- Department of Chemical, Biological and Environmental Engineering-Autonomous University of Barcelona
  • Yüksek lisans: Marmara Universitesi/Fen Bilimleri Enstitüsü/Biyomühendislik
  • Lisans: Marmara Üniversitesi/Mühendislik Fakültesi/Biyomühendislik
PROJELER

o Gıda endüstrisinde kullanılmak üzere bakteri kaynaklı a-amilazın dogal organik polimere immobilizasyonu ve optimizasyonu (TUBİTAK 2209 B) Akademik Danışman (2024Devam ediyor)
o Yeni α-Amilazın İfade Etkinliğinin AOX Prömotoru ile P. pastoris'te Değerlendirilmesi (GTU-BAP) Araştırmacı (2022-2023)
o Priestia megaterium' dan a-Amilaz Enziminin E. koli ile İfadesi ve Karakterizasyonu" (TUBİTAK 2209 B) Akademik Danışman (2023-2024)
o Biyobenzer mab: Yerli Olarak Geliştirilmesi ve Üretilmesi, (TUBİTAK-1007) Bursiyer (2017-2018).
o Gümüş-Kurkumin Nanokompozitlerinin Yeşil Sentez Yöntemi ile Eldesi ve Karakterizasyonu, (TUBİTAK-3001) Bursiyer (2019-2021).