Prof. Dr. Elif Damla ARISAN
Biyoteknoloji enstitüsü

(262) (0262) 605 2615
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Çalışma alanları
Hücre ölümü, hücre sinyal yolakları, moleküler kanser biyolojisi, hücre moleküler biyolojisi, mTOR, AMPK
Detaylı özgeçmiş


1: Arisan ED, Rencuzogullari O, Cieza-Borrella C, Miralles Arenas F, Dwek M, Lange S, Uysal-Onganer P. MiR-21 Is Required for the Epithelial-Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. Int J Mol Sci. 2021 Feb 4;22(4):1557. doi: 10.3390/ijms22041557. PMID: 33557112.

2: Rencuzogulları O, Yerlikaya PO, Gürkan AÇ, Arısan ED, Telci D. Palbociclib negatively regulates fatty acid synthesis due to upregulation of AMPKα and miR-33a levels to increase apoptosis in Panc-1 and MiaPaCa-2 cells. Biotechnol Appl Biochem. 2021 Feb 3. doi: 10.1002/bab.2113. Epub ahead of print. PMID:

3: Lange S, Arisan ED, Grant GH, Uysal-Onganer P. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. Viruses. 2021 Jan 16;13(1):117. doi: 10.3390/v13010117. PMID: 33467206; PMCID: PMC7830670.

4. Bortecine Sevgin, Mervenur Coban, Özge Rencuzogullari, Ajda Coker Gurkan, Pinar Obakan Yerlikaya, Pinar Uysal Onganer, Elif Damla ARISAN. AMPK is the key target for the CDK4/6 inhibitors mediated therapeutic responses in PANC-1 and MIA PaCa-2 pancreatic cancer cell lines.

5. Mortoglou M, Wallace D, Buha Djordjevic A, Djordjevic V, Arisan ED, Uysal-Onganer P. MicroRNA-Regulated Signaling Pathways: Potential Biomarkers for Pancreatic Ductal Adenocarcinoma. Stresses. 2021; 1(1):30-47.

6. Maria Mortoglou; Zoey Kathleen Tabin; Elif Damla Arisan; Hemant M Kocher; Pinar Uysal Onganer. Non-Coding RNAs in Pancreatic Ductal Adenocarcinoma: New Approaches for Better Diagnosis and Therapy Accepted in Translational Oncology.

7. Obakan Yerlikaya P, Arısan ED, Coker Gurkan A, Okumus OO, Yenigun T, Ozbey U, Kara M, Palavan Unsal N. Epibrassinolide prevents tau hyperphosphorylation via GSK3β inhibition in vitro and improves Caenorhabditis elegans lifespan and motor deficits in combination with roscovitine. Amino Acids. 2021 Aug 13. doi: 10.1007/s00726-021-03027-2. Epub ahead of print. PMID: 34386848.

8. Coker-Gurkan A, Can E, Sahin S, Obakan-Yerlikaya P, Arisan ED. Atiprimod triggered apoptotic cell death via acting on PERK/eIF2α/ATF4/CHOP and STAT3/NF-ΚB axis in MDA-MB-231 and MDA-MB-468 breast cancer cells. Mol Biol Rep. 2021 Jun;48(6):5233-5247. doi: 10.1007/s11033-021-06528-1. Epub 2021 Jul 9. PMID: 34244887.

9. Coker-Gurkan A, Koyuncu K, Yerlikaya PO, Arisan ED. miR27a, a fine-tuning molecule, interacts with growth hormone (GH) signaling and ornithine decarboxylase (ODC) via targeting STAT5. Amino Acids. 2021 Nov 26. doi: 10.1007/s00726-021-03101-9. Epub ahead of print. PMID: 34825975.

10. Ozfiliz-Kilbas P, Sonmez O, Obakan-Yerlikaya P, Coker-Gurkan A, Palavan-Ünsal N, Uysal-Onganer P, Arisan ED. In Vitro Investigations of miR-33a Expression in Estrogen Receptor-Targeting Therapies in Breast Cancer Cells. Cancers (Basel). 2021 Oct 23;13(21):5322. doi: 10.3390/cancers13215322. PMID: 34771486; PMCID: PMC8582455.

11. Ozfiliz Kılbaş P ve ark. CRISPR/Cas9-Mediated Bag-1 knockout increased mesenchymal characteristics of MCF-7 cells via Akt hyperactivation-mediated actin cytoskeleton remodeling (Baskıya kabul-PONE-D-21-06156)

12. PELİN ÖZFİLİZ KILBAŞ, GİZEM ALKURT, PINAR OBAKAN YERLİKAYA, AJDA ÇOKER GÜRKAN, GİZEM DİNLER DOĞANAY, ELİF DAMLA ARISAN. The comparison of differentially expressed microRNAs in Bag-1 deficient and wild type MCF-7 breast cancer cells by small RNA sequencing Available online: 14.11.2021
DOI: 10.3906/biy-2109-48 (This number will become active after the manuscript has been selected for inclusion in an issue.)

13. Ajda Çoker Gürkan et al. Synthesis and characterization of novel ssDNA X-Aptamers Targeting Growth Hormone Releasing Hormone (GHRH) (Baskıya kabul PONE-D-21-00439).


1.Proinflammatory cytokine profile is critical in autocrine GH-triggered curcumin resistance engulf by atiprimod cotreatment in MCF-7 and MDA-MB-231 breast cancer cells. Coker-Gurkan A, Ozakaltun B, Akdeniz BS, Ergen B, Obakan-Yerlikaya P, Akkoc T, Arisan ED. Mol Biol Rep. 2020 Nov;47(11):8797-8808. doi: 10.1007/s11033-020-05928-z. Epub 2020 Oct 31.PMID: 33130987

2.Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways. Ozfiliz Kilbas P, Sonmez O, Uysal-Onganer P, Coker Gurkan A, Obakan Yerlikaya P, Arisan ED. Biology (Basel). 2020 Oct 1;9(10):320. doi: 10.3390/biology9100320.PMID: 33019717 Free PMC article.

3.Putative Roles for Peptidylarginine Deiminases in COVID-19.
Arisan ED, Uysal-Onganer P, Lange S. Int J Mol Sci. 2020 Jun 30;21(13):4662. doi: 10.3390/ijms21134662. PMID: 32629995 Free PMC article.

4.Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells.Arisan ED, Rencuzogullari O, Keskin B, Grant GH, Uysal-Onganer P.Biology (Basel). 2020 Jun 27;9(7):142. doi: 10.3390/biology9070142.PMID: 32605008 Free PMC article.

5.The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities.Arisan ED, Dart A, Grant GH, Arisan S,Cuhadaroglu S, Lange S, Uysal-Onganer P. Viruses. 2020 Jun 4;12(6):614. doi: 10.3390/v12060614. PMID: 32512929 Free PMC article.

6.Epibrassinolide-induced autophagy occurs in an Atg5-independent manner due to endoplasmic stress induction in MEF cells.Adacan K, Obakan-Yerlikaya P, Arisan ED, Coker-Gurkan A, Kaya RI, Palavan-Unsal N.Amino Acids. 2020 Jul;52(6-7):871-891. doi: 10.1007/s00726-020-02857-w. Epub 2020 May 24.PMID: 32449072

7. Upregulated Wnt-11 and miR-21 Expression Trigger Epithelial Mesenchymal Transition in Aggressive Prostate Cancer Cells. Arisan ED, Rencuzogullari O, Freitas IL, Radzali S, Keskin B, Kothari A, Warford A, Uysal-Onganer P.Biology (Basel). 2020 Mar 9;9(3):52. doi: 10.3390/biology9030052.PMID: 32182839 Free PMC article.


1.The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells.Arisan ED, Akar RO, Rencuzogullari O, Obakan Yerlikaya P, Coker Gurkan A, Akın B, Dener E, Kayhan E, Palavan Unsal N. Prostate Int. 2019 Dec;7(4):156-165. doi: 10.1016/j.prnil.2019.09.003. Epub 2019 Nov 14.PMID: 31970141 Free PMC article.

2. Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways.Coker-Gurkan A, Ayhan-Sahin B, Keceloglu G, Obakan-Yerlikaya P, Arisan ED, Palavan-Unsal N.J Cell Biochem. 2019 Dec;120(12):19749-19763. doi: 10.1002/jcb.29281. Epub2019 Jul 3.PMID: 31270852

3.Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial-mesenchymal transition in Panc-1 and MiaPaCa-2 pancreatic cancer cells.Rencuzogulları O, Yerlikaya PO, Gürkan AÇ, Arısan ED, Telci D.
J Cell Biochem. 2020 Jan;121(1):508-523. doi: 10.1002/jcb.29249. Epub 2019Jul 1.PMID: 31264276

4.Bag-1 silencing enhanced chemotherapeutic drug-induced apoptosis in MCF-7 breast cancer cells affecting PI3K/Akt/mTOR and MAPK signaling pathways.
Kilbas PO, Akcay IM, Doganay GD, Arisan ED.
Mol Biol Rep. 2019 Feb;46(1):847-860. doi: 10.1007/s11033-018-4540-x. Epub 2019 Jan 19. PMID: 30661182


1.Curcumin prevented human autocrine growth hormone (GH) signaling mediated NF-κB activation and miR-183-96-182 cluster stimulated epithelial mesenchymal transition in T47D breast cancer cells.
Coker-Gurkan A, Bulut D, Genc R, Arisan ED, Obakan-Yerlikaya P, Palavan-Unsal N. Mol Biol Rep. 2019 Feb;46(1):355-369. doi: 10.1007/s11033-018-4479-y. Epub 2018 Nov 23.PMID: 30467667

2. Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells.
Arisan ED, Ergül Z, Bozdağ G, Rencüzoğulları Ö, Çoker-Gürkan A, Obakan-Yerlikaya P, Coşkun D, Palavan-Ünsal N.Mol Biol Rep. 2018 Dec;45(6):2175-2184. doi: 10.1007/s11033-018-4378-2. Epub 2018 Nov 8.PMID: 30406888

3.Inhibition of extracellular signal-regulated kinase potentiates the apoptotic and antimetastatic effects of cyclin-dependent kinase inhibitors on metastatic DU145 and PC3 prostate cancer cells.Rencüzoğullari Ö, Arısan ED, Obakan Yerlikaya P, Çoker Gürkan A, Keskin B, Palavan Ünsal N.
J Cell Biochem. 2019 Apr;120(4):5558-5569. doi: 10.1002/jcb.27840. Epub 2018 Oct 15.PMID: 30320903

4. Biological responses of ultrafine grained pure titanium and their sand blasted surfaces.Günay-Bulutsuz A, Berrak Ö, Yeprem HA, Arisan ED, Yurci ME.
Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:382-388. doi: 10.1016/j.msec.2018.05.056. Epub 2018 May 18.PMID: 30033268

5. Cyclin-dependent kinase inhibitors, roscovitine and purvalanol, induce apoptosis and autophagy related to unfolded protein response in HeLa cervical cancer cells.Ozfiliz-Kilbas P, Sarikaya B, Obakan-Yerlikaya P, Coker-Gurkan A, Arisan ED, Temizci B, Palavan-Unsal N.
Mol Biol Rep. 2018 Oct;45(5):815-828. doi: 10.1007/s11033-018-4222-8. Epub 2018 Jul 5.PMID: 29978381

6. Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-κB signaling and polyamine metabolism in breast cancer cells.Coker-Gurkan A, Celik M, Ugur M, Arisan ED, Obakan-Yerlikaya P, Durdu ZB, Palavan-Unsal N.Amino Acids. 2018 Aug;50(8):1045-1069. doi: 10.1007/s00726-018-2581-z. Epub 2018 May 16.PMID: 29770869

7. Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.Gurkan AC, Arisan ED, Yerlikaya PO, Ilhan H, Unsal NP.Cell Oncol (Dordr). 2018 Jun;41(3):297-317. doi: 10.1007/s13402-017-0369-x. Epub 2018 Feb 28.PMID: 29492901

1. Serum antioxidant enzyme levels are decreased in patients with urinary calcium oxalate stones.Cakir OO, Culha MG, Arisan S, Arisan ED, Altin M, Ward S, Zengi O, Ergenekon E.Urol J. 2017 Jul 2;14(4):4015-4019.PMID: 28670668

2. Calreticulin is a fine tuning molecule in epibrassinolide-induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells.Obakan-Yerlikaya P, Arisan ED, Coker-Gurkan A, Adacan K, Ozbey U, Somuncu B, Baran D, Palavan-Unsal N.Mol Carcinog. 2017 Jun;56(6):1603-1619. doi: 10.1002/mc.22616. Epub 2017 Feb 16.
PMID: 28112451


1.DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery.Akyol Z, Çoker-Gürkan A, Arisan ED, Obakan-Yerlikaya P, Palavan-Ünsal N.Biomed Pharmacother. 2016 Dec;84:2029-2041. doi: 10.1016/j.biopha.2016.11.016. Epub

2.mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.
Berrak O, Arisan ED, Obakan-Yerlikaya P, Coker-Gürkan A, Palavan-Unsal N.
Apoptosis. 2016 Oct;21(10):1158-78. doi: 10.1007/s10495-016-1275-9.
PMID: 27484210


1. The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells. Berrak Ö, Akkoç Y, Arısan ED, Çoker-Gürkan A, Obakan-Yerlikaya P, Palavan-Ünsal N. Biomed Pharmacother. 2016 Feb;77:150-60. doi: 10.1016/j.biopha.2015.12.007. Epub 2015 Dec 29.PMID: 26796279

2. SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells. Obakan P, Barrero C, Coker-Gurkan A, Arisan ED, Merali S, Palavan-Unsal N.PLoS One. 2015 Sep 9;10(9):e0135788. doi: 10.1371/journal.pone.0135788. eCollection 2015.PMID: 26353013 Free PMC article.

3. Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells.Coskun D, Obakan P, Arisan ED, Çoker-Gürkan A, Palavan-Ünsal N.Exp Cell Res. 2015 Oct 15;338(1):10-21. doi: 10.1016/j.yexcr.2015.08.015.Epub 2015 Aug 28.
PMID: 26318418

4.Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells.Ozfiliz P, Kizilboga T, Demir S, Alkurt G, Palavan-Unsal N, Arisan ED, Dinler-Doganay G. Cell Biochem Funct. 2015 Jul;33(5):293-307. doi: 10.1002/cbf.3114. Epub 2015 Jul

5. Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells.
Akkoç Y, Berrak Ö, Arısan ED, Obakan P, Çoker-Gürkan A, Palavan-Ünsal N.
Biomed Pharmacother. 2015 Apr;71:161-71. doi: 10.1016/j.biopha.2015.02.029. Epub 2015 Mar 4.PMID: 25960232

6.Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells.
Coker-Gürkan A, Arisan ED, Obakan P, Akalın K, Özbey U, Palavan-Unsal N.
Oncol Rep. 2015 Jun;33(6):2761-70. doi: 10.3892/or.2015.3918. Epub 2015 Apr 21.PMID: 25901510

7.Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (≥ 40 years of age).Coker-Gurkan A, Coskun D, Arisan ED, Obakan P, Soylu Ö, Unsal NP.
Mol Med Rep. 2015 Jul;12(1):1356-62. doi: 10.3892/mmr.2015.3521. Epub 2015 Mar 20.PMID: 25815703

8. Polyamines modulate the roscovitine-induced cell death switch decision autophagy vs. apoptosis in MCF-7 and MDA-MB-231 breast cancer cells.
Arisan ED, Akkoç Y, Akyüz KG, Kerman EM, Obakan P, Çoker-Gürkan A, Palavan Ünsal N.Mol Med Rep. 2015 Jun;11(6):4532-40. doi: 10.3892/mmr.2015.3303. Epub 2015 Feb 4.PMID: 25650699


1. Roscovitine-treated HeLa cells finalize autophagy later than apoptosis by downregulating Bcl‑2.Coker-Gurkan A, Arisan ED, Obakan P, Ozfiliz P, Kose B, Bickici G, Palavan-Unsal N.Mol Med Rep. 2015 Mar;11(3):1968-74. doi: 10.3892/mmr.2014.2902. Epub 2014 Nov 7.
PMID: 25378060

2.Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells.
Çoker-Gürkan A, Arisan ED, Obakan P, Palavan-Unsal N.
Amino Acids. 2015 Jan;47(1):87-100. doi: 10.1007/s00726-014-1851-7. Epub 2014 Oct 14.PMID: 25311224

3.Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells.Obakan P, Arisan ED, Coker-Gurkan A, Palavan-Unsal N.Prostate. 2014 Dec;74(16):1622-33. doi: 10.1002/pros.22879. Epub 2014 Sep 11.
PMID: 25214240

4.Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells.Coker-Gurkan A, Arisan ED, Obakan P, Guvenir E, Unsal NP.Exp Cell Res. 2014 Oct 15;328(1):87-98. doi: 10.1016/j.yexcr.2014.07.022.Epub 2014 Aug 1.PMID: 25088259

5.Bag-1L is a stress-withstand molecule prevents the downregulation of Mcl-1 and c-Raf under control of heat shock proteins in cisplatin treated HeLa cervix cancer cells.Ozfiliz P, Arisan ED, Coker-Gurkan A, Obakan P, Eralp TN, Dinler-Doganay G, Palavan-Unsal N.Asian Pac J Cancer Prev. 2014;15(11):4475-82. doi: 10.7314/apjcp.2014.15.11.4475.
PMID: 24969872

6.Lack of evidence for the association of ornithine decarboxylase (+316 G>A), spermidine/spermine acetyl transferase (-1415 T>C) gene polymorphisms with calcium oxalate stone disease.Coker-Gürkan A, Arisan S, Arisan ED, Unsal NP.
Biomed Rep. 2014 Jan;2(1):69-74. doi: 10.3892/br.2013.184. Epub 2013 Oct 21.

7. Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells.
Obakan P, Arısan ED, Özfiliz P, Çoker-Gürkan A, Palavan-Ünsal N.
Mol Biol Rep. 2014 Jan;41(1):145-54. doi: 10.1007/s11033-013-2847-1. Epub 2013 Nov 5.PMID: 24190492


1.Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines.Obakan P, Arisan ED, Calcabrini A, Agostinelli E, Bolkent S, Palavan-Unsal N.Amino Acids. 2014 Mar;46(3):553-64. doi: 10.1007/s00726-013-1574-1. Epub 2013 Aug 21.PMID: 23963538
2. Inhibition of polyamine oxidase prevented cyclin-dependent kinase inhibitor-induced apoptosis in HCT 116 colon carcinoma cells.
Gürkan AC, Arisan ED, Obakan P, Palavan-Ünsal N.
Apoptosis. 2013 Dec;18(12):1536-47. doi: 10.1007/s10495-013-0885-8.
PMID: 23892915
3. CDK inhibitors induce mitochondria-mediated apoptosis through the activation of polyamine catabolic pathway in LNCaP, DU145 and PC3 prostate cancer cells.Arisan ED, Obakan P, Coker-Gurkan A, Calcabrini A, Agostinelli E, Unsal NP.
Curr Pharm Des. 2014;20(2):180-8. doi: 10.2174/13816128113199990029.
PMID: 23701543
4. Association between IL-1RN VNTR, IL-1β -511 and IL-6 (-174, -572, -597) gene polymorphisms and urolithiasis.
Çoker Gurkan A, Arisan S, Arisan ED, Sönmez NC, Palavan Ünsal N.
Urol Int. 2013;91(2):220-6. doi: 10.1159/000345786. Epub 2013 Jan 26.
PMID: 23363559


Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells.
Arisan ED, Obakan P, Coker A, Palavan-Unsal N.
Mol Med Rep. 2012 May;5(5):1323-9. doi: 10.3892/mmr.2012.786. Epub 2012 Feb 13.
PMID: 22344475

Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.
Çoker A, Arısan ED, Palavan-Ünsal N.
Mol Med Rep. 2012 Apr;5(4):1037-42. doi: 10.3892/mmr.2012.768. Epub 2012 Jan 30.
PMID: 22294330 Free PMC article.


Polyamine depletion enhances the roscovitine-induced apoptosis through the activation of mitochondria in HCT116 colon carcinoma cells.
Arısan ED, Coker A, Palavan-Ünsal N.
Amino Acids. 2012 Feb;42(2-3):655-65. doi: 10.1007/s00726-011-1040-x. Epub 2011 Aug 2.
PMID: 21809075

Raman micro-spectroscopic analysis of cultured HCT116 colon cancer cells in the presence of roscovitine.
Akyuz S, Ozel AE, Balci K, Akyuz T, Coker A, Arisan ED, Palavan-Unsal N, Ozalpan A.
Spectrochim Acta A Mol Biomol Spectrosc. 2011 May;78(5):1540-7. doi: 10.1016/j.saa.2011.01.046. Epub 2011 Feb 2.
PMID: 21345720

AKSU SENA, (2019). Crohn hastalığında vitamin D reseptörü ve interlökin gen ailesi tek nükleotit polimorfizmlerinin belirlenmesi, İstanbul Kültür Üniversitesi-Lisansüstü Eğitim Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

AL-ANI SOHAIB WISAM MADDAH, (2019). Bakteri temelli kanser terapötik mekanizmalarının incelenmesi, İstanbul Kültür Üniversitesi-Lisansüstü Eğitim Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

GÜLTEKİN ESRA NUR, (2019). Serotonin'in terapotik potansiyelinin mcf-7 meme kanseri hücrelerinde incelenmesi, İstanbul Kültür Üniversitesi-Lisansüstü Eğitim Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

NEBİLER ESRA, (2019). Obezite tedavisinde kullanılan orlistat'ın prostat kanseri pc3 ve pnt1a hücre hatlarında ampka hedefi ile ilişkili global protein ifade düzeylerinin 2d-dıge yöntemi ile tanımlanması, İstanbul Kültür Üniversitesi-Lisansüstü Eğitim Enstitüsü-Moleküler Biyokimya ve Genetik Anabilim Dalı

NEZİR AYÇA ECE, (2017). Sikline bağımlı kinaz inhibitörlerinin doğal tip ve Atg5 ifadesinden yoksun MEF hücrelerinde terapotik etkilerinin araştırılması, İstanbul Kültür Üniversitesi-Fen Bilimleri Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

DURSUN ŞENAY, (2017). Serotonın uygulaması yapılan MCF-7 ve MDA-MB-231 meme kanseri hücrelerinde hücre sağ kalım ve ölüm kararının incelenmesi, İstanbul Kültür Üniversitesi-Fen Bilimleri Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

GÜMÜŞKAPTAN ÇAĞRI, (2015). CDK inhibitörlerinin mTOR susturması gerçekleştirilen LNCaP, DU145 ve PC3 prostat kanseri hücrelerinde terapotik etkisinin incelenmesi, İstanbul Kültür Üniversitesi-;Fen Bilimleri Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

BERRAK ÖZGE, (2014). mTOR sinyal yolağının rapamycin ile baskılanması durumunda CDK inhibitörlerinin terapotik etkilerinin LNCaP, DU145 ve PC3 prostat kanseri hücrelerinde incelenmesi, İstanbul Kültür Üniversitesi-Fen Bilimleri Enstitüsü-Moleküler Biyoloji ve Genetik Anabilim Dalı

ÖZFİLİZ PELİN, (2013). Bag-1 silencing enhanced cisplatin or paclitaxel-induced apoptotsis in MCF-7 breast cancer cells, İstanbul Teknik Üniversitesi-Fen Bilimleri Enstitüsü-leri Teknolojiler Anabilim Dalı

  • Doktora: Sabancı Üniversitesi, Biyolojik Bilimler ve Biyomühendislik
  • Yüksek lisans: Marmara Üniversitesi, Tıbbi Biyoloji ve Genetik ABD
  • Lisans: Marmara Üniversitesi, Biyoloji Öğretmenliği Bölümü

Harvard Üniversitesi, Kanser Biyoloji ve Terapotik CBT
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