Journal Article

Uluslararası hakemli dergilerde yayınlanan makaleler

Özdemir, F. İ., Şükür, G., Yiğit, B.M.,Tülek, A. (2026). Mediator-assisted tetracycline transformation and dye decolorization by a thermostable recombinant laccase from Yersinia enterocolitica. Enzyme and Microbial Technology, 110903.

2.Sukur, G., Tülek, A., Servili, B., Tülek, G. S., Yildirim, D., Özdemir, F. İ. (2026). Structure-guided engineering of Geobacillus kaustophilus L-asparaginase with improved functional and stability characteristics for acrylamide mitigation. International Journal of Biological Macromolecules, 151461.

3.Tülek, A., Poyraz, Y., Şükür, G., Paçal, N., Özdemir, F. İ., Yildirim, D., Eşsiz, Ş. (2025). Engineering of Geobacillus kaustophilus lipase for enhanced catalytic efficiency and methanol
tolerance in biodiesel production from sunflower oil. International Journal of Biological Macromolecules, 148467.

4.Tülek, A., Şükür, G., Özdemir, F. İ., Varan, N. E., Yıldırım, D. (2025). Immobilization of L-asparaginase on genipin and divinyl sulfone cross-linked multi-walled carbon nanotubes and
silica supports for acrylamide mitigation. Food Chemistry, 491, 145268. https://doi.org/10.1016/j.foodchem.2025.145268

5. Özdemir, F. İ., Servili, B., Demirtaş, Ö., Şükür, G., Tülek, A.,Yıldırım, D. (2025). Integrating computational and experimental insights into osmolyte-driven activation of Geobacillus
kaustophilus L-asparaginase for acrylamide mitigation. Journal of Molecular
Liquids, 423(1), 127072. https://doi.org/10.1016/j.molliq.2025.127072

6.Özdemir, F. İ., Karaaslan, B., Tülek, A., Yıldırım, D. (2024). Covalent immobilization of recombinant L-asparaginase from Geobacillus kaustophilus on ReliZyme supports for mitigation of acrylamide. Biocatalysis and Biotransformation, 42(3), 426–439. https://doi.org/10.1080/10242422.2023.2257351

7. Özdemir, F. İ., Tülek, A., Karaaslan, B., Yıldırım, D. (2024). Evaluation of multi-walled carbon nanotubes bearing aldehyde groups of different lengths for the immobilization of Geobacillus kaustophilus L-asparaginase. Molecular Catalysis, 555, 113903. https://doi.org/10.1016/j.mcat.2024.113903

8.Özdemir, F. İ., Karaaslan, B.,Tülek, A., Yücebilgiç, G., &Yıldırım, D. (2023). Immobilization of recombinant L-asparaginase from Geobacillus kaustophilus on magnetic MWCNT-nickel composites. Process Biochemistry, 127, 10–20. https://doi.org/10.1016/j.procbio.2023.01.021

9.Özdemir, F. İ., Orhan, M. D., Atasavum, Z. T., Tülek, A. (2022). Biochemical characterization and detection of antitumor activity of L-asparaginase from thermophilic Geobacillus kaustophilus DSM 7263T. Protein Expression and Purification, 199, 106146. https://doi.org/10.1016/j.pep.2022.106146

10. Özdemir, F. İ., Tülek, A., Erdoğan, D. (2021). Identification and heterologous production of a lipase from Geobacillus kaustophilus DSM 7263T and tailoring its N-terminal by a His-tag
epitope. The Protein Journal, 40(3), 436–447. https://doi.org/10.1134/S0003683820060186

11. Yılmaz, H., Ergenekon, P., Özdemir, F. İ., Özkan, M. (2020). Affinity tag effect on the salt rejection potential of Halomonas elongata aquaporin incorporated in thin film nanocomposite
membrane. Protein Expression and Purification, 173, 105664. https://doi.org/10.1016/j.pep.2020.105664

12. Tülek, A., Özdemir, F. İ.,&#160;&#160;Ramadhan, S. S. (2020). Cloning, expression and characterization of membrane bound FtsH protease of Geobacillus kaustophilus. Applied Biochemistry and Microbiology, 56(6), 678–684. https://doi.org/10.1007/s10930-021-09987-4</span>

13. Kocabıyık, S., Özdemir, F. İ., Doğan, S., &amp;amp; Zwickle, P. (2010). Molecular cloning and co-expression of Thermoplasma volcanium proteasome subunit genes. Protein Expression and Purification, 70(3), 223–230. https://doi.org/10.1016/j.pep.2010.05.004

14. Kocabıyık , S &amp;amp;amp; Özdemir, F. İ.(2006). Purification and characterization of an intracellular chymotrypsin-like serine protease from Thermoplasma volcanium. Bioscience, Biotechnology, and
Biochemistry, 70(1), 126–134. https://doi.org/10.1271/bbb.70.126

Ulusal hakemli dergilerde yayınlanan makaleler

1. Özdemir, F. İ., Aydın, B., &amp;amp;Tülek, A. (2023). Investigation of the siderophore production and associated heavy metal accumulation potential of Brevibacillus laterosporus 301/İK3 Hacettepe
Journal of Biology and Chemistry, 51(3), 317-325.

2. Özdemir Fİ, Korkmaz T, (2023). Çevresel Koşulların Termofilik Geobacillus kaustophilus’ da Biyofilm Oluşumu Üzerinde Etkisi.&amp;#160; Iğdır&amp;#160;Institute of Science and Technology, 13(3), 1562-1572.

Uluslararası hakemli dergilerde yayınlanan kitap bölümü

Özdemir, F. İ., &amp;amp;amp;amp; Tülek, A. (2025). Microbial Metal Magicians: Siderophore Alchemy in Environmental Cleanup. In Global Perspectives of Toxic Metals in Bio Environs: Volume 2: Biotransformation, Remediation and Technological Advances (pp. 123-160). Cham: Springer Nature Switzerland.

Ders Kodu	Ders Adı

Didem Müge Orhan. Termofilik Geobacillus kaustophilus L-Asparajinazın Antitümör Etkisinin Belirlenmesi; M.Sc. Thesis.; Gebze Institute of Technology 2016 (Ongoing).

Salim Ramadhan. Cloning and Expression of Membrane Bound FtsH protease of Geobacillus kaustophilus in Escherichia coli; M.Sc. Thesis. Gebze Institute of Technology 2016 (Graduated).

Bahadır Aydın. Production of siderophore from Geobacillus kaustophilus under the Cd stress. M.Sc. Thesis. Gebze Institute of Technology 2014 (Graduated).

Enis Güney. Characterization of siderophore production from Bacillus cereus. M.Sc. Thesis. Gebze Institute of Technology 2014 (Graduated).

Ahmet Tülek. Cloning and expression of Geobacillus kaustophilus ftsH gene. M.Sc. Thesis. Gebze Institute of Technology 2014 (Graduated).

Tuba Korkmaz. Effects of environmental stress conditions on biofilm formation by thermophilic Geobacillus kaustophilus. M.Sc. Thesis. Gebze Institute of Technology 2012 (Graduated).

Davut Erdoğan. Cloning, expression and characterization of a lipase from thermophilic bacterium Geobacillus kaustophilus. M.Sc. Thesis. Gebze Institute of Technology 2012 (Graduated).

Hatice Zişan Asal. Purification and characterization of recombinant Geobacillus kaustophilus protein Lon from E. coli.M.Sc. Thesis. Gebze Institute of Technology 2011(Graduated).

Haluk Camcı. Cloning and expression of lon geneof Geobacillus kaustophilus. M.Sc. Thesis. Gebze Institute of Technology 2009 (Graduated).

Gonca Altın. Purification and characterization of recombinant Geobacillus kaustophilus protein HslV and HslU from E. coli. M.Sc. Thesis. Gebze Institute of Technology 2009 (Graduated).

Kemal Avican. Cloning and expression of hslV and hslU genes of Geobacillus kaustophilus. Gebze Institute of Technology 2009 (Graduated).

• Doktora: Orta Doğu Teknik Üniversitesi Fen-Edebiyat Fakültesi Biyoloji
• Yüksek lisans: Illinois Institute of Technology Master of Science Biology
• Lisans: Ege Üniversitesi Fen Fakültesi Biyoloji