GTU Academic's Joint Invention Gets Patented

December 1, 2025 - GTU Office of Press and Public Relations
 

A significant scientific invention, also contributed by Assoc. Prof. Mehmet Özbil, a faculty member at GTU, marks a breakthrough in the fight against antibiotic-resistant bacteria.

The invention titled “Microorganism-Targeted Nanoformulations Containing Antimicrobial Component(s)”, jointly developed by Assoc. Prof. Mehmet Özbil, a faculty member at Gebze Technical University (GTU) Institute of Biotechnology, and researchers from the Departments of Molecular Biology and Genetics and Bioengineering at Yıldız Technical University, has been accepted by the Turkish Patent and Trademark Office (TÜRKPATENT).

Designed entirely within the “Computational Biochemistry Laboratory” of the GTU Institute of Biotechnology, the invention focuses on creating nanoformulations that contain peptides inspired by and synthesized from the receptor-binding proteins (RBPs) of bacteriophages. These nanoformulations demonstrate strong efficacy against target bacteria.

2 to 9 Times More Effective Treatment: Scientific studies have shown that the developed formulation enhances vancomycin and oxacillin treatments applied to antibiotic-resistant bacteria, making them 2 to 9 times more effective than conventional treatments that do not include nanoformulations.

Reduced Side Effects and Controlled Release: Research findings indicate not only increased antibacterial efficacy but also reduced toxicity and more controlled release of the drugs within the body.

This innovative nanoformulation-based agent offers significant potential as a solution to the rapidly growing global problem of antibiotic resistance. With its registration by TÜRKPATENT, this invention paves the way for commercialization processes and aims to make a meaningful contribution to human health.